Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 11/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29383470 | 0.98 | P2RX4 (0.40) | P2RX4LMNATSHRMAPK1SCN4A | |
| Hydrochloric Acid SCHEMBL3122652 | 0.98 | P2RX4 (0.40) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL27498070 | 0.78 | KMT2A (0.41) | P2RX4LMNASCN9AP2RX1P2RX3 | |
| SCHEMBL27769491 | 0.78 | SLC6A1 (0.37) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL9030241 | 0.76 | P2RX4 (0.37) | P2RX4LMNAMAPK1P2RX1P2RX3 | |
| SCHEMBL9030962 | 0.75 | MAPT (0.38) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL20987115 | 0.74 | MAPK1 (0.35) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL3687782 | 0.74 | P2RX4 (0.44) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL7333680 | 0.72 | P2RX4 (0.40) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11534924 | 0.71 | KMT2A (0.41) | LMNATSHRMAPK1SCN4ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2034967-B1 | ORAL PHARMACEUTICAL COMPOSITION OF A POORLY WATER-SOLUBLE ACTIVE SUBSTANCE | ABBOTT HEALTHCARE PRODUCTS BV (NL) | 2011-05-18 | — | — | EP | claimed |
| EP-1848439-B1 | ORAL IMMEDIATE RELEASE FORMULATION OF A POORLY WATERSOLUBLE ACTIVE SUBSTANCE | SOLVAY PHARM BV (NL) | 2010-03-10 | — | — | EP | claimed |
| US-20070292503-A1 | ORAL PHARMACEUTICAL COMPOSITION OF POORLY WATER-SOLUBLE ACTIVE SUBSTANCE | SOLVAY PHARMACEUTICALS B.V. (NL) | 2007-12-20 | — | — | US | claimed |
| CN-101087612-A | Oral immediate release formulation of a poorly watersoluble active substance | SOLVAY PHARM BV (NL) | 2007-12-12 | — | — | CN | claimed |
| EP-1848439-A1 | ORAL IMMEDIATE RELEASE FORMULATION OF A POORLY WATERSOLUBLE ACTIVE SUBSTANCE | Solvay Pharmaceuticals B.V. (NL) | 2007-10-31 | — | — | EP | claimed |
| US-7273860-B2 | Method and pharmaceutical compositions for treating or inhibiting renal dysfunctions, diseases or disorders, particularly in diabetic patients | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-09-25 | — | — | US | claimed |
| WO-2007102171-A2 | NOVEL SALTS OF 1H-1-BENZAZEPINE-1-ACETIC ACID, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION | PANACEA BIOTEC LTD (IN) | 2007-09-13 | — | — | WO | claimed |
| EP-1476196-B1 | ORAL SOLID SOLUTION FORMULATION OF A POORLY WATER-SOLUBLE ACTIVE SUBSTANCE | SOLVAY PHARM BV (NL) | 2006-11-22 | — | — | EP | claimed |
| US-20060159748-A1 | Oral immediate release formulation of a poorly water-soluble active substance | PANACEA BIOTEC LTD. (IN) | 2006-07-20 | — | — | US | claimed |
| WO-2006067150-A1 | ORAL IMMEDIATE RELEASE FORMULATION OF A POORLY WATERSOLUBLE ACTIVE SUBSTANCE | SOLVAY PHARMACEUTICALS B.V. (NL) | 2006-06-29 | — | — | WO | claimed |
| JP-10101565-A | — | — | None | — | — | JP | disclosed |
| CN-111808011-B | High penetration composition and its application | 泰飞尔生物医药(苏州)有限公司 | 2024-02-27 | — | — | CN | disclosed |
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | TECHFIELDS PHARMA CO., LTD (CN) | 2023-07-27 | — | — | US | disclosed |
| US-11541029-B2 | High penetration compositions and their applications | TECHFIELDS PHARMA CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| CN-108676076-A | The method for preparing guanosine cyclic mono-phosphate agonist | 辛纳吉制药公司 | 2018-10-19 | — | — | CN | disclosed |
| WO-2000048601-A1 | MEDICAMENT FOR TREATING HYPERTENSION | SOLVAY PHARMACEUTICALS GMBH (DE) | 2000-08-24 | — | — | WO | disclosed |
| US-5783573-A | Pharmaceuticals which promote gastrointestinal blood circulation | SOLVAY PHARMACEUTICALS GMBH (DE) | 1998-07-21 | — | — | US | disclosed |
| JP-H10101565-A | EMPLOYMENT OF BENZAZEPINE-N-ACETIC ACID DERIVATIVE FOR PRODUCING MEDICINAL PREPARATION FOR TREATING AND PREVENTING GASTROINTESTINAL HEMATOGENOUS INJURY | SOLVAY PHARMACEUT GMBH | 1998-04-21 | — | — | JP | disclosed |
| EP-0830863-A1 | Drugs for increasing gastrointestinal blood supply | Solvay Pharmaceuticals GmbH (DE) | 1998-03-25 | — | — | EP | disclosed |
| EP-0292923-A2 | Piperidine compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060159748-A1 | Oral immediate release formulation of a poorly water-soluble active substance | SUCNR1, SI, TREH | P2RX4 2357/4885LMNA 1337/4885TSHR 2926/4885 |
| US-20070292503-A1 | ORAL PHARMACEUTICAL COMPOSITION OF POORLY WATER-SOLUBLE ACTIVE SUBSTANCE | KCNN1, CACNA2D1, KCNN2 | P2RX4 2402/4885LMNA 1598/4885TSHR 4127/4885 |
| US-11541029-B2 | High penetration compositions and their applications | SLC19A1, HIRA, SLC43A1 | P2RX4 3191/4885LMNA 1775/4885TSHR 4827/4885 |
| US-20230233516-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | SLC5A7, SLC19A1, SLC43A1 | P2RX4 1657/4885LMNA 2635/4885TSHR 4760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.