SCHEMBL2776972

SCHEMBL2776972

OCCCCSSSSCCCCO

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3680523 0.97 LMNA (0.38) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL8368422 0.93 TSHR (0.37) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL3688120 0.90 LMNA (0.38) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL721781 0.90 TSHR (0.39) TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL3679045 0.86 SMN1; SMN2 (0.39) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL3723747 0.83 LMNA (0.42) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL2458373 0.83 LMNA (0.42) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL7902914 0.83 LMNA (0.42) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL3579746 0.83 LMNA (0.42) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL4449694 0.83 TSHR (0.39) TSHRSMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3211017-A1 POLYURETHANE Compagnie Générale des Etablissements Michelin (FR) 2017-08-30 EP disclosed
EP-2115033-B1 POLYURETHANE MICHELIN & CIE (FR) 2017-05-17 EP disclosed
EP-2175001-B1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION FOR POLARIZING PLATES AND POLARIZING PLATE HAVING PRESSURE-SENSITIVE ADHESIVE LAYER SOKEN KAGAKU KK (JP) 2014-04-30 EP disclosed
US-20130287982-A1 POLYURETHANE MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-10-31 US disclosed
US-8512834-B2 Polyurethane COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2013-08-20 US disclosed
CN-101370870-B Epoxy resin molding material for sealing and electronic component device HITACHI CHEMICAL CO LTD 2012-07-18 CN disclosed
US-8217130-B2 Curable composition and method for producing the same CEMEDINE CO., LTD. (JP) 2012-07-10 US disclosed
US-8188194-B2 Adhesive for polarizing plate and polarizing plate having adhesive layer SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) 2012-05-29 US disclosed
EP-2093252-B1 Curing composition and method for producing curing composition CEMEDINE CO LTD (JP) 2012-05-16 EP disclosed
CN-101563394-B Polyurethane MICHELIN SOC TECH 2012-04-11 CN disclosed
WO-2008077151-A1 POLYURETHANE SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-06-26 WO disclosed
US-20060293456-A1 Curable composition and method for producing the same CEMEDINE CO., LTD. (JP) 2006-12-28 US disclosed
CN-1823133-A Curable composition and method for producing curable composition CEMEDINE CO LTD (JP) 2006-08-23 CN disclosed
EP-1650257-A1 CURING COMPOSITION AND METHOD FOR PRODUCING CURING COMPOSITION CEMEDINE CO., LTD. (JP) 2006-04-26 EP disclosed
US-6861486-B2 Catalyst for bulk polymerization SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) 2005-03-01 US disclosed
US-20030023012-A1 CATALYST FOR BULK POLYMERIZATION SOKEN CHEMICAL & ENGINEERING CO., LTD. 2003-01-30 US disclosed
US-6489412-B1 A CATALYST FOR BULK POLYMERIZATION COMPRISING AN ORGANOMETALLIC COMPOUND REPRESENTED BY SPECIFIED FORMULA AND A THIOL IS PROVIDED. THE SPECIFIED ORGANOMETALLIC COMPOUND IS A METALLOCENE COMPOUND SUCH AS TITANOCENE OR ZIRCONOCENE. SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) 2002-12-03 US disclosed
EP-0552376-B1 PRODUCTION OF POLYMER HYDROXYLATED AT BOTH TERMINALS, COMPOSITION CONTAINING SAID POLYMER AND ITS USE, AND POLYMER DERIVED FROM SAID COMPOSITION AND ITS USE NIPPON CATALYTIC CHEM IND (JP) 1999-01-13 EP disclosed
US-5391665-A Catalyzed polymerization in the presence of a dihydroxypolysulfide compound NIPPON SHOKUBAI CO., LTD. (JP) 1995-02-21 US disclosed
EP-0552376-A1 PRODUCTION OF POLYMER HYDROXYLATED AT BOTH TERMINALS, COMPOSITION CONTAINING SAID POLYMER AND ITS USE, AND POLYMER DERIVED FROM SAID COMPOSITION AND ITS USE NIPPON SHOKUBAI CO., LTD. (JP) 1993-07-28 EP disclosed