Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449694 | 0.93 | TSHR (0.39) | TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2776972 | 0.90 | TSHR (0.37) | TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3680523 | 0.87 | LMNA (0.38) | TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL331112 | 0.85 | TDP1 (0.38) | TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13307640 | 0.84 | — | — | |
| SCHEMBL8368422 | 0.83 | TSHR (0.37) | TSHRTDP1ALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL10506011 | 0.81 | TDP1 (0.35) | TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3688120 | 0.80 | LMNA (0.38) | TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8848234 | 0.80 | — | — | |
| SCHEMBL2109116 | 0.77 | TDP1 (0.47) | TSHRTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716393-B2 | Functionalized polysulfide silica coupling agents and silica reinforced rubber composition for tire components | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-06 | — | — | US | claimed |
| EP-1191057-B1 | Silica reinforced rubber composition prepared with pretreated silica and article of manufacture | GOODYEAR TIRE & RUBBER (US) | 2004-12-01 | — | — | EP | claimed |
| US-6713549-B1 | UTILIZING NONALKOXYSILANE CONTAINING COUPLING AGENT; REDUCED ALCOHOL BYPRODUCT EVOLUTION | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-03-30 | — | — | US | claimed |
| EP-1191057-A1 | Silica reinforced rubber composition prepared with pretreated silica and article of manufacture | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-03-27 | — | — | EP | claimed |
| EP-0791622-B1 | Silica reinforced rubber composition and tire with tread thereof | GOODYEAR TIRE & RUBBER (US) | 1999-12-01 | — | — | EP | claimed |
| US-5733963-A | SILICA COUPLER COMPRISED OF 3,3'-TETRATHIODIPROPANOL POLYSULFIDE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-03-31 | — | — | US | claimed |
| EP-0791622-A1 | Silica reinforced rubber composition and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-08-27 | — | — | EP | claimed |
| JP-9227721-A | — | — | None | — | — | JP | disclosed |
| US-9790352-B2 | Rubber blends containing silicic acid and comprising additives containing sulphur | LANXESS DEUTSCHLAND GMBH (DE) | 2017-10-17 | — | — | US | disclosed |
| US-9783658-B2 | Rubber mixtures containing silicic acid and sulfur-containing additives | LANXESS DEUTSCHLAND GMBH (DE) | 2017-10-10 | — | — | US | disclosed |
| US-9758642-B2 | Rubber mixtures containing silicic acid and sulfur-containing additives | LANXESS DEUTSCHLAND GMBH (DE) | 2017-09-12 | — | — | US | disclosed |
| EP-3211017-A1 | POLYURETHANE | Compagnie Générale des Etablissements Michelin (FR) | 2017-08-30 | — | — | EP | disclosed |
| EP-2115033-B1 | POLYURETHANE | MICHELIN & CIE (FR) | 2017-05-17 | — | — | EP | disclosed |
| US-5733963-A | SILICA COUPLER COMPRISED OF 3,3'-TETRATHIODIPROPANOL POLYSULFIDE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-03-31 | — | — | US | disclosed |
| US-5733963-A | SILICA COUPLER COMPRISED OF 3,3'-TETRATHIODIPROPANOL POLYSULFIDE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-03-31 | — | — | US | disclosed |
| JP-H09227721-A | SILICA-REINFORCED RUBBER COMPOSITION AND TIRE HAVING ITS TREAD | GOODYEAR TIRE & RUBBER CO:THE | 1997-09-02 | — | — | JP | disclosed |
| EP-0791622-A1 | Silica reinforced rubber composition and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-08-27 | — | — | EP | disclosed |
| EP-0791622-A1 | Silica reinforced rubber composition and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-08-27 | — | — | EP | disclosed |
| US-5391665-A | Catalyzed polymerization in the presence of a dihydroxypolysulfide compound | NIPPON SHOKUBAI CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0552376-A1 | PRODUCTION OF POLYMER HYDROXYLATED AT BOTH TERMINALS, COMPOSITION CONTAINING SAID POLYMER AND ITS USE, AND POLYMER DERIVED FROM SAID COMPOSITION AND ITS USE | NIPPON SHOKUBAI CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |