SCHEMBL4449694

SCHEMBL4449694

OCCCSSSCCCO

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL721781 0.93 TSHR (0.39) TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL8368422 0.90 TSHR (0.37) TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL3688120 0.87 LMNA (0.38) TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL331112 0.85 TDP1 (0.38) TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL2776972 0.83 TSHR (0.37) TSHRTDP1ALDH1A1SMN1; SMN2
Bromide SCHEMBL10506011 0.81 TDP1 (0.35) TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL3680523 0.80 LMNA (0.38) TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL13307640 0.78
SCHEMBL2108625 0.77
SCHEMBL12103936 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024060640-A1 MODIFIED EPOXIDIZED RUBBER, PREPARATION METHOD THEREFOR, AND USE THEREOF 江苏麒祥高新材料有限公司 2024-03-28 WO claimed
WO-2024060640-A1 MODIFIED EPOXIDIZED RUBBER, PREPARATION METHOD THEREFOR, AND USE THEREOF 江苏麒祥高新材料有限公司 2024-03-28 WO disclosed
EP-3211017-A1 POLYURETHANE Compagnie Générale des Etablissements Michelin (FR) 2017-08-30 EP disclosed
EP-2115033-B1 POLYURETHANE MICHELIN & CIE (FR) 2017-05-17 EP disclosed
US-8889802-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2014-11-18 US disclosed
US-20130287982-A1 POLYURETHANE MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-10-31 US disclosed
US-20120130040-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2012-05-24 US disclosed
US-20090012233-A1 Epoxy Resin Molding Material for Sealing and Electronic Component Device HITACHI CHEMICAL CO., LTD. (JP) 2009-01-08 US disclosed
EP-0552376-B1 PRODUCTION OF POLYMER HYDROXYLATED AT BOTH TERMINALS, COMPOSITION CONTAINING SAID POLYMER AND ITS USE, AND POLYMER DERIVED FROM SAID COMPOSITION AND ITS USE NIPPON CATALYTIC CHEM IND (JP) 1999-01-13 EP disclosed
US-5391665-A Catalyzed polymerization in the presence of a dihydroxypolysulfide compound NIPPON SHOKUBAI CO., LTD. (JP) 1995-02-21 US disclosed
EP-0552376-A1 PRODUCTION OF POLYMER HYDROXYLATED AT BOTH TERMINALS, COMPOSITION CONTAINING SAID POLYMER AND ITS USE, AND POLYMER DERIVED FROM SAID COMPOSITION AND ITS USE NIPPON SHOKUBAI CO., LTD. (JP) 1993-07-28 EP disclosed
EP-0162261-B1 SULPHUR CONTAINING POLYETHERURETHANS, PROCESS FOR THEIR PREPARATION AND THEIR USE BAYER AG (DE) 1987-08-19 EP disclosed
US-4214061-A FROM AN ACRYLATE POLYMER, ISOCYANATE-TERMINATED POLYURETHANE PREPOLYMER, AND AN ALKANEDIOL; CURED THE B. F. GOODRICH COMPANY (US) 1980-07-22 US disclosed