Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 4/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28761558 | 0.86 | MAPT (0.57) | SLC6A9ALDH1A1LMNAMAPTSLC6A5 | |
| SCHEMBL27925825 | 0.85 | MAPT (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL28806302 | 0.85 | ALDH1A1 (0.59) | WDR5ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL993182 | 0.83 | LMNA (0.65) | SLC6A9WDR5ALDH1A1LMNAMAPT | |
| SCHEMBL30890284 | 0.83 | LMNA (0.65) | SLC6A9WDR5ALDH1A1LMNAMAPT | |
| SCHEMBL27851910 | 0.83 | MEN1 (0.46) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL27830588 | 0.83 | ALDH1A1 (0.42) | WDR5ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL27648774 | 0.82 | PHGDH (0.46) | ALDH1A1MAPTHTT | |
| SCHEMBL28331620 | 0.82 | KCNJ1 (0.44) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL27730809 | 0.81 | MAPT (0.46) | WDR5MAPTSMN1; SMN2HTTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103443102-A | Bicyclic carboxamide inhibitors of kinases | ABBVIE INC | 2013-12-11 | — | — | CN | disclosed |
| CN-102796099-A | Imidazoquinolines as lipid kinase inhibitors | NOVARTIS AG | 2012-11-28 | — | — | CN | disclosed |
| CN-101495477-A | Imidazoquinolines as lipid kinase inhibitors | NOVARTIS AG (CH) | 2009-07-29 | — | — | CN | disclosed |