SCHEMBL277698

SCHEMBL277698

C=CCc1c(C(=O)O)cc(S(=O)(=O)O)c(C(=O)O)c1CC=C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.36
CASP1 P29466 2/20 0.36
CASP7 P55210 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 3/20 0.35
GAA P10253 2/20 0.35
TSHR P16473 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2D6 P10635 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CA12 O43570 3/20 0.32
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA3 P07451 3/20 0.32
CA4 P22748 3/20 0.32
CA6 P23280 3/20 0.32
CA7 P43166 3/20 0.32
CA9 Q16790 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7162007 0.88 HSD17B10 (0.37) HSD17B10CASP1CASP7ALDH1A1TDP1
SCHEMBL5329793 0.82 KDM4E (0.35) HSD17B10CASP1CASP7ALDH1A1TDP1
SCHEMBL2805682 0.79 KDM4E (0.35) HSD17B10CASP1CASP7ALDH1A1TDP1
SCHEMBL787323 0.78 GAA (0.38) HSD17B10ALDH1A1KDM4EGAATSHR
SCHEMBL16246768 0.77 GAA (0.41) HSD17B10ALDH1A1KDM4EGAATSHR
SCHEMBL277699 0.74 CYP2D6 (0.35) HSD17B10KDM4EGAATSHRSMN1; SMN2
SCHEMBL28380141 0.74 CYP2D6 (0.35) HSD17B10KDM4EGAATSHRSMN1; SMN2
SCHEMBL278362 0.74 CYP2D6 (0.35) HSD17B10KDM4EGAATSHRSMN1; SMN2
SCHEMBL9280152 0.74 CYP2D6 (0.35) HSD17B10KDM4EGAATSHRSMN1; SMN2
SCHEMBL271102 0.72 KDM4E (0.35) HSD17B10KDM4EGAATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220010171-A1 Release Coating Compositions and Articles Therefrom 3M INNOVATIVE PROPERTIES COMPANY 2022-01-13 US claimed
WO-2020128969-A1 RELEASE COATING COMPOSITIONS AND ARTICLES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-06-25 WO claimed
US-20030236379-A1 Sulfonated polyester-siloxane resin XEROX CORPORATION 2003-12-25 US claimed
US-6664015-B1 Diacid, diol, and carbinol carboxy terminated polydimethylsiloxane comonomers with at least one being a sulfonate salt; paints, toners, protective coatings XEROX CORPORATION 2003-12-16 US claimed
US-6017671-A TONER COMPOSITION COMPRISING A POLYESTER RESIN WITH HYDROPHILIC MOIETIES AND HYDROPHOBIC END GROUPS, COLORANT, WAX, CHARGE ADDITIVE, AND SURFACE ADDITIVES; TRIBOELECTRICAL PROPERTIES XEROX CORPORATION (US) 2000-01-25 US claimed
US-5348832-A Toner compositions XEROX CORPORATION (US) 1994-09-20 US claimed
EP-3578370-B1 AQUEOUS INK COMPOSITION COMPRISING POLYISOPRENE, PROCESS AND PRINTING PROCESS XEROX CORP (US) 2024-07-10 EP disclosed
EP-3578371-B1 WATERBORNE CLEAR INK COMPOSITIONS, PROCESS AND PRINTING PROCESS XEROX CORP (US) 2024-07-10 EP disclosed
EP-3578614-B1 SULFONATED POLYESTER INK XEROX CORP (US) 2023-12-13 EP disclosed
US-11815851-B2 Toner compositions and additives XEROX CORPORATION (US) 2023-11-14 US disclosed
EP-3633459-B1 SURFACE ADDITIVE INFRARED TAGGANT TONER XEROX CORP (US) 2023-11-08 EP disclosed
EP-4266124-A1 TONER COMPOSITION Xerox Corporation (US) 2023-10-25 EP disclosed
US-20230333495-A1 Toner Composition U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2023-10-19 US disclosed
US-20040142266-A1 Toner compositions and processes thereof XEROX CORPORATION 2004-07-22 US disclosed
US-20030236379-A1 Sulfonated polyester-siloxane resin XEROX CORPORATION 2003-12-25 US disclosed
US-6664015-B1 Diacid, diol, and carbinol carboxy terminated polydimethylsiloxane comonomers with at least one being a sulfonate salt; paints, toners, protective coatings XEROX CORPORATION 2003-12-16 US disclosed
US-20030211035-A1 Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same XEROX CORPORATION 2003-11-13 US disclosed
EP-1055971-A1 Toner, developer compositions, process of imaging, polyester and process for preparation of polyester Xerox Corporation (US) 2000-11-29 EP disclosed
US-6017671-A TONER COMPOSITION COMPRISING A POLYESTER RESIN WITH HYDROPHILIC MOIETIES AND HYDROPHOBIC END GROUPS, COLORANT, WAX, CHARGE ADDITIVE, AND SURFACE ADDITIVES; TRIBOELECTRICAL PROPERTIES XEROX CORPORATION (US) 2000-01-25 US disclosed
US-5348832-A Toner compositions XEROX CORPORATION (US) 1994-09-20 US disclosed