SCHEMBL7162007

SCHEMBL7162007

C=CCc1c(C(=O)O)cc(S(=O)(=O)O)c(CC=C)c1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.37
KDM4E B2RXH2 3/20 0.37
GAA P10253 2/20 0.37
TSHR P16473 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 3/20 0.36
CASP1 P29466 2/20 0.36
CASP7 P55210 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2D6 P10635 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CA12 O43570 3/20 0.32
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA3 P07451 3/20 0.32
CA4 P22748 3/20 0.32
CA6 P23280 3/20 0.32
CA7 P43166 3/20 0.32
CA9 Q16790 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277698 0.88 HSD17B10 (0.36) HSD17B10KDM4EGAATSHRSMN1; SMN2
SCHEMBL16246768 0.84 GAA (0.41) HSD17B10KDM4EGAATSHRSMN1; SMN2
SCHEMBL2805682 0.82 KDM4E (0.35) HSD17B10KDM4EGAATSHRSMN1; SMN2
SCHEMBL5329793 0.82 KDM4E (0.35) HSD17B10KDM4EGAATSHRSMN1; SMN2
SCHEMBL7139648 0.78 GAA (0.38) HSD17B10KDM4EGAATSHRSMN1; SMN2
SCHEMBL5178996 0.78 GAA (0.38) HSD17B10KDM4EGAATSHRSMN1; SMN2
SCHEMBL5173168 0.76 HSD17B10 (0.42) HSD17B10KDM4EALDH1A1CASP1CASP7
SCHEMBL3227961 0.76 KDM4E (0.37) HSD17B10KDM4EGAATSHRSMN1; SMN2
SCHEMBL28894036 0.75 HSD17B10 (0.41) HSD17B10KDM4EALDH1A1CASP1CASP7
SCHEMBL1073390 0.75 ALDH1A1 (0.38) HSD17B10KDM4EALDH1A1CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5407981-A Reacting ester of dibasic acid, short chain diol,long chain polyglycol, alkali salt of dialkylsulfoisophthalate, stabilizers and alkali salt of phenol; for extrusion, blow molding CHEIL SYNTHETICS INC. (KR) 1995-04-18 US claimed
EP-0605260-A1 Preparation of polyether ester elastomers having high melt viscosities and crystallization CHEIL SYNTHETICS INC. (KR) 1994-07-06 EP claimed
JP-2003238680-A METHOD FOR PRODUCING NYLON 6 COPOLYMER CONTAINING SULFONIC ACID COMONOMER IND TECHNOL RES INST 2003-08-27 JP disclosed
US-5407981-A Reacting ester of dibasic acid, short chain diol,long chain polyglycol, alkali salt of dialkylsulfoisophthalate, stabilizers and alkali salt of phenol; for extrusion, blow molding CHEIL SYNTHETICS INC. (KR) 1995-04-18 US disclosed
EP-0605260-A1 Preparation of polyether ester elastomers having high melt viscosities and crystallization CHEIL SYNTHETICS INC. (KR) 1994-07-06 EP disclosed
EP-0605260-A1 Preparation of polyether ester elastomers having high melt viscosities and crystallization CHEIL SYNTHETICS INC. (KR) 1994-07-06 EP disclosed
EP-0257411-A2 Method for the production of optically active enamines or the corresponding aldehydes F. HOFFMANN-LA ROCHE AG (CH) 1988-03-02 EP disclosed
EP-0105016-B1 POLYISOPHTHALATE AND COPOLYMERS THEREOF HAVING REDUCED CYCLIC DIMER CONTENT, AND A PROCESS FOR MAKING THE SAME THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-01-21 EP disclosed
EP-0076226-B1 HIGH MELT STRENGTH ELASTOMERIC COPOLYESTERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-05-07 EP disclosed
EP-0105016-A1 Polyisophthalate and copolymers thereof having reduced cyclic dimer content, and a process for making the same THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-04-04 EP disclosed
US-4424337-A Polyisophthalate and copolymers thereof having reduced cyclic dimer content, and a process for making the same THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-01-03 US disclosed
US-4390687-A POLYESTERETHER COPOLYMERS, 1A METAL 5-SULFO-ISOPHTHALATE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-06-28 US disclosed
EP-0076226-A1 High melt strength elastomeric copolyesters THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-04-06 EP disclosed
US-4150946-A ABRASION RESISTANT TEXTILES RHONE-POULENC INDUSTRIES (FR) 1979-04-24 US disclosed