Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3033286 | 0.84 | PDE2A (0.39) | MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL5356483 | 0.81 | AR (0.46) | ARTSHR | |
| SCHEMBL6222140 | 0.77 | CYP3A4 (0.44) | EPHX2KMT2A | |
| SCHEMBL13105395 | 0.74 | ALDH1A1 (0.39) | EPHX2MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL22357162 | 0.73 | KMT2A (0.36) | EPHX2MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL21201386 | 0.71 | ACHE (0.35) | MEN1KMT2ATSHRMAPK1MAPT | |
| SCHEMBL98000 | 0.70 | TDP1 (0.42) | MEN1KMT2AALOX15MAPTGAA | |
| SCHEMBL2718835 | 0.69 | CYP3A4 (0.48) | ARALOX15TSHRMAPK1MAPT | |
| SCHEMBL5368422 | 0.69 | CYP1A2 (0.36) | EPHX2MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL29598324 | 0.69 | CYP3A4 (0.48) | ARALOX15TSHRMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101578260-A | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-11 | — | — | CN | disclosed |