Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952493 | 0.83 | ESR1 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29380184 | 0.82 | PDE2A (0.42) | ALDH1A1MAPTKIF11MTORNPSR1 | |
| SCHEMBL624000 | 0.82 | PDE2A (0.42) | ALDH1A1MAPTKIF11MTORNPSR1 | |
| SCHEMBL28191882 | 0.80 | PDE2A (0.41) | ALDH1A1MAPTKIF11MTORNPSR1 | |
| SCHEMBL13105395 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPTGAAHSD17B10KIF11 | |
| SCHEMBL17709790 | 0.79 | MEN1 (0.47) | HSD17B10MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29509486 | 0.79 | MEN1 (0.47) | HSD17B10MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29598324 | 0.78 | CYP3A4 (0.48) | CYP3A4ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL5350038 | 0.78 | KDM1A (0.36) | KIF11 | |
| SCHEMBL2718835 | 0.78 | CYP3A4 (0.48) | CYP3A4ALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169955-B2 | Perfluoroisopropylbenzene derivative | NIHON NOHYAKU CO., LTD. (JP) | 2007-01-30 | — | — | US | disclosed |
| US-20050113567-A1 | Perfluoroisopropylbenzene derivative | NIHON NOHYAKU CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| US-20030187233-A1 | PERFLUOROISOPROPYBENZENE DERIVATIVE | NIHON NOHYAKU CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1253128-A1 | PERFLUOROISOPROPYLBENZENE DERIVATIVES | Nihon Nohyaku Co., Ltd. (JP) | 2002-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187233-A1 | PERFLUOROISOPROPYBENZENE DERIVATIVE | AFF1, CBR1, RER1 | CYP1A2 156/4885CYP3A4 223/4885CYP2D6 98/4885 |
| US-20050113567-A1 | Perfluoroisopropylbenzene derivative | FFAR3, CBR3, HCAR3 | CYP1A2 467/4885CYP3A4 197/4885CYP2D6 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.