Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18822335 | 0.74 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2BAKR1C1HDAC4 | |
| SCHEMBL11216766 | 0.74 | GRIN1 (0.50) | GRIN1GRIN2AGRIN2BAKR1C1MEN1 | |
| SCHEMBL8115016 | 0.73 | OPRM1 (0.54) | GRIN1GRIN2ASMN1; SMN2 | |
| SCHEMBL12494953 | 0.72 | GRIN1 (0.43) | GRIN1GRIN2AGRIN2BAKR1C1HDAC4 | |
| SCHEMBL18794819 | 0.71 | GRIN1 (0.51) | GRIN1GRIN2AGRIN2BAKR1C1MEN1 | |
| SCHEMBL1653538 | 0.70 | CCR2 (0.33) | — | |
| SCHEMBL14214917 | 0.69 | HDAC9 (0.57) | AKR1C1HDAC4MEN1KMT2A | |
| SCHEMBL2313192 | 0.68 | GRIN1 (0.55) | GRIN1GRIN2AGRIN2BAKR1C1MEN1 | |
| Hydrochloric Acid SCHEMBL6818616 | 0.68 | GRIN1 (0.51) | GRIN1GRIN2AGRIN2BMEN1KMT2A | |
| SCHEMBL28222493 | 0.68 | GRIN1 (0.44) | GRIN1GRIN2AGRIN2BAKR1C1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646655-A | Imidazolidine carboxamide derivatives as lipase and phospholipase inhibitors | SANOFI AVENTIS FR | 2010-02-10 | — | — | CN | disclosed |