Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.34 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28958044 | 0.86 | KMT2A (0.54) | RAB9ANPC1MGLLHSD11B1KMT2A | |
| Tert-Butyl Formate SCHEMBL27597018 | 0.86 | MGLL (0.40) | RAB9ANPC1LMNAMGLLKMT2A | |
| Tert-Butyl Formate SCHEMBL28017487 | 0.86 | MEN1 (0.39) | RAB9ANPC1KMT2AMEN1CYP2D6 | |
| SCHEMBL4192969 | 0.83 | CES2 (0.46) | RAB9ANPC1LMNAMGLLHSD11B1 | |
| Hydrochloric Acid SCHEMBL28507556 | 0.82 | MEN1 (0.46) | RAB9ANPC1LMNAMGLLHSD11B1 | |
| Trifluoroacetic Acid SCHEMBL30548828 | 0.77 | HSD11B1 (0.43) | RAB9ANPC1LMNAMGLLHSD11B1 | |
| Tert-Butyl Formate SCHEMBL28024240 | 0.77 | TDP1 (0.41) | RAB9ANPC1LMNATDP1MAPK1 | |
| Tert-Butyl Formate SCHEMBL27890349 | 0.74 | TDP1 (0.48) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28875402 | 0.73 | MEN1 (0.54) | LMNAMGLLKMT2AMEN1CYP2D6 | |
| Tert-Butyl Formate SCHEMBL27713287 | 0.73 | TDP1 (0.56) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101454328-A | Novel mch receptor antagonists | LILLY CO ELI (US) | 2009-06-10 | — | — | CN | disclosed |