Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.60 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.55 |
| ▸ | SYK | P43405 | 2/20 | 0.49 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770274 | 0.90 | EGFR (0.74) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL7809216 | 0.86 | EGFR (0.81) | EGFRNOX4RGS12ALDH1A1LCK | |
| Lysine SCHEMBL27787583 | 0.85 | EGFR (0.46) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL27770270 | 0.83 | EGFR (0.60) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL27749184 | 0.83 | EGFR (0.60) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL3300413 | 0.83 | PPARA (0.73) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL19664973 | 0.82 | PYGL (0.51) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL7809127 | 0.81 | NOX4 (0.78) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL27858209 | 0.80 | EGFR (0.54) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL27770338 | 0.79 | APP (0.58) | EGFRNOX4RGS12ALDH1A1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101792399-A | Aminosalicylic acid derivative lysine complex salt, preparation method and application thereof | UNIV NANJING MEDICAL | 2010-08-04 | — | — | CN | disclosed |
| CN-101492384-A | Uses of aminosalicylic acid derivative as neuroprotective agent | UNIV NANJING MEDICAL (CN) | 2009-07-29 | — | — | CN | disclosed |