Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.74 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.74 |
| ▸ | RGS12 | O14924 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | LCK | P06239 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | PPARA | Q07869 | 1/20 | 0.67 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.67 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.57 |
| ▸ | SYK | P43405 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770271 | 0.90 | EGFR (0.60) | EGFRNOX4RGS12ALDH1A1LCK | |
| Lavendustin C SCHEMBL1821516 | 0.85 | EGFR (1.00) | EGFRNOX4RGS12ALDH1A1LCK | |
| Lavendustin C SCHEMBL30569227 | 0.85 | EGFR (1.00) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL27858209 | 0.84 | EGFR (0.54) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL29391100 | 0.84 | PPARA (0.92) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL609562 | 0.84 | PPARA (0.92) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL27787480 | 0.83 | EGFR (0.74) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL7803944 | 0.82 | NOX4 (1.00) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL31227828 | 0.81 | PPARA (1.00) | EGFRNOX4RGS12ALDH1A1LCK | |
| SCHEMBL31227865 | 0.80 | PPARA (0.70) | EGFRNOX4RGS12ALDH1A1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102516107-A | N-benzylaniline derivatives and application thereof | UNIV NANJING MEDICAL | 2012-06-27 | — | — | CN | disclosed |
| CN-101492384-A | Uses of aminosalicylic acid derivative as neuroprotective agent | UNIV NANJING MEDICAL (CN) | 2009-07-29 | — | — | CN | disclosed |