Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27749268 | 0.99 | OPRM1 (0.40) | OPRM1OPRD1OPRK1GAASLC6A9 | |
| SCHEMBL27770304 | 0.74 | CHRM1 (0.39) | OPRM1OPRD1OPRK1SLC6A9KMT2A | |
| Hydrochloric Acid SCHEMBL27749266 | 0.73 | ATM (0.39) | OPRM1OPRD1OPRK1GAAKMT2A | |
| SCHEMBL4297116 | 0.67 | OPRM1 (0.38) | OPRM1OPRD1OPRK1SLC6A9KMT2A | |
| Prodilidine SCHEMBL26140 | 0.64 | LMNA (0.70) | OPRM1OPRD1OPRK1GAAKMT2A | |
| SCHEMBL8550616 | 0.64 | OPRM1 (0.43) | OPRM1OPRD1OPRK1GAACYP2D6 | |
| Prodilidine SCHEMBL120377 | 0.63 | LMNA (0.72) | OPRM1OPRD1OPRK1GAAKMT2A | |
| SCHEMBL1190560 | 0.63 | LMNA (0.41) | KMT2ALMNACHRM1ALDH1A1 | |
| SCHEMBL1190461 | 0.63 | LMNA (0.41) | KMT2ALMNACHRM1ALDH1A1 | |
| SCHEMBL1189315 | 0.63 | LMNA (0.41) | KMT2ALMNACHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479243-A | Glycine transporter-1 inhibitors | AMGEN INC (US) | 2009-07-08 | — | — | CN | claimed |