Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27749266 | 0.99 | ATM (0.39) | CHRM1OPRK1OPRM1OPRD1ATM | |
| SCHEMBL27770310 | 0.74 | OPRM1 (0.41) | CHRM1OPRK1OPRM1OPRD1LMNA | |
| Biphenyl SCHEMBL27679403 | 0.74 | KCNN4 (0.37) | CHRM1OPRK1OPRM1OPRD1ATM | |
| SCHEMBL4297116 | 0.73 | OPRM1 (0.38) | OPRK1OPRM1OPRD1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27749268 | 0.73 | OPRM1 (0.40) | CHRM1OPRK1OPRM1OPRD1ATM | |
| SCHEMBL16858836 | 0.67 | ESR1 (0.37) | CHRM1OPRK1ATMSMN1; SMN2CYP3A4 | |
| SCHEMBL27593886 | 0.66 | NR1H2 (0.46) | — | |
| SCHEMBL10688395 | 0.65 | OPRK1 (0.40) | CHRM1OPRK1OPRM1OPRD1ATM | |
| SCHEMBL10691957 | 0.63 | CHRNB2 (0.41) | CHRM1OPRK1OPRM1OPRD1ATM | |
| SCHEMBL16599372 | 0.61 | CHRM1 (0.36) | CHRM1ATMLMNANPSR1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479243-B | Glycine transporter-1 inhibitors | AMGEN INC | 2013-01-02 | — | — | CN | claimed |
| CN-101479243-A | Glycine transporter-1 inhibitors | AMGEN INC (US) | 2009-07-08 | — | — | CN | claimed |