Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
| ▸ | ELANE | P08246 | 3/20 | 0.58 |
| ▸ | PRTN3 | P24158 | 3/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | METAP2 | P50579 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191912 | 0.96 | WDR5 (0.68) | WDR5LMNAKDM4EHTTNPC1 | |
| SCHEMBL3560029 | 0.89 | WDR5 (0.59) | WDR5LMNAKDM4EHTTNPC1 | |
| SCHEMBL3562391 | 0.88 | WDR5 (0.58) | WDR5LMNAKDM4EHTTNPC1 | |
| SCHEMBL3552696 | 0.87 | WDR5 (0.57) | WDR5LMNAKDM4EHTTNPC1 | |
| SCHEMBL23200377 | 0.84 | METAP2 (0.76) | WDR5LMNAKDM4ENPC1ALDH1A1 | |
| SCHEMBL4651039 | 0.84 | PTGES2 (0.66) | WDR5LMNAKDM4EHTTNPC1 | |
| SCHEMBL30486834 | 0.83 | LMNA (0.70) | LMNAKDM4EHTTGAAALDH1A1 | |
| SCHEMBL2477690 | 0.83 | LMNA (0.70) | LMNAKDM4EHTTGAAALDH1A1 | |
| SCHEMBL23200374 | 0.82 | METAP2 (0.70) | WDR5LMNAKDM4ENPC1ALDH1A1 | |
| SCHEMBL3558860 | 0.82 | WDR5 (0.57) | WDR5LMNAHTTTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646647-A | New methylenebisphenyl compounds useful in the treatment of inflammation | BIOLIPOX AB SE | 2010-02-10 | — | — | CN | disclosed |