Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27749333 | 0.76 | GRM2 (0.41) | L3MBTL1ALDH1A1SMN1; SMN2GRM2KMT2A | |
| SCHEMBL27749332 | 0.75 | AVPR2 (0.36) | L3MBTL1ALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL27770355 | 0.67 | — | — | |
| SCHEMBL28305131 | 0.63 | EHMT2 (0.42) | ALDH1A1KDM4EPOLBSMN1; SMN2KMT2A | |
| SCHEMBL27949939 | 0.62 | P2RX7 (0.45) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL28552309 | 0.61 | ATM (0.58) | ALDH1A1KDM4EPOLBHTTKMT2A | |
| SCHEMBL21847081 | 0.61 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL27473060 | 0.60 | — | — | |
| SCHEMBL3982942 | 0.60 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL3605369 | 0.58 | GRM2 (0.49) | L3MBTL1ALDH1A1MAPTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495458-A | Substituted arylimidazolone and triazolone as inhibitors of vasopressin receptors | BAYER HEALTHCARE AG (DE) | 2009-07-29 | — | — | CN | disclosed |