Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590686 | 0.81 | SMN1; SMN2 (0.56) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| SCHEMBL10228326 | 0.76 | UBE2T (0.50) | RAB9ANPC1SMN1; SMN2UBE2TASIC3 | |
| SCHEMBL8193282 | 0.76 | SMN1; SMN2 (0.61) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| SCHEMBL3113690 | 0.74 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MAPTGAA | |
| SCHEMBL27462967 | 0.74 | MAPT (0.61) | RAB9ANPC1SMN1; SMN2UBE2TASIC3 | |
| SCHEMBL27770511 | 0.72 | RAB9A (0.37) | RAB9ANPC1SMN1; SMN2UBE2TASIC3 | |
| SCHEMBL19941789 | 0.72 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2UBE2TASIC3 | |
| SCHEMBL14858755 | 0.72 | KEAP1 (0.64) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL6067860 | 0.72 | ABL1 (0.65) | RAB9ANPC1SMN1; SMN2DYRK1A | |
| SCHEMBL507587 | 0.71 | CSF1R (0.39) | RAB9ANPC1SMN1; SMN2UBE2TASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101631786-A | Novel JNK inhibitors | SCHERING CORP | 2010-01-20 | — | — | CN | disclosed |