Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1815170 | 0.87 | MAPT (0.33) | SMARCA2SMARCA4PBRM1MAPTMEN1 | |
| SCHEMBL27749338 | 0.83 | NCF1 (0.35) | NCF1ALDH1A1KDM4E | |
| SCHEMBL27749353 | 0.81 | NCF1 (0.37) | NCF1ALDH1A1 | |
| SCHEMBL16814993 | 0.80 | NCF1 (0.54) | SMARCA2SMARCA4PBRM1NCF1MAPT | |
| SCHEMBL27770383 | 0.79 | DRD2 (0.43) | NCF1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL27865306 | 0.77 | NCF1 (0.38) | NCF1MAPTALDH1A1KDM4E | |
| SCHEMBL188544 | 0.77 | SLC18A3 (0.38) | SMARCA2SMARCA4PBRM1MAPTMEN1 | |
| SCHEMBL2479088 | 0.73 | KDM4E (0.39) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL14758902 | 0.71 | NCF1 (0.48) | SMARCA2SMARCA4PBRM1NCF1MAPT | |
| SCHEMBL1814332 | 0.71 | GAA (0.36) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101432284-A | Dihydropyrazolopyrimidinone derivative | BANYU PHARMA CO LTD (JP) | 2009-05-13 | — | — | CN | disclosed |