Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1815031 | 0.79 | DRD2 (0.46) | DRD2DRD3MAPTNPSR1HTR6 | |
| SCHEMBL28862177 | 0.79 | DRD2 (0.46) | DRD2DRD3MAPTNPSR1HTR6 | |
| SCHEMBL27770395 | 0.79 | SMARCA2 (0.35) | MAPTNCF1MEN1KMT2AKDM4E | |
| SCHEMBL27865306 | 0.75 | NCF1 (0.38) | DRD2MAPTNCF1CYP3A4HTR2A | |
| SCHEMBL27749338 | 0.75 | NCF1 (0.35) | NCF1HTR1AADRA1AOPRM1HRH3 | |
| SCHEMBL27749331 | 0.75 | SLC18A3 (0.46) | DRD2HTR6SLC18A3SLC6A4HRH1 | |
| SCHEMBL17599744 | 0.74 | ALDH1A1 (0.52) | DRD2DRD3MAPTNPSR1MAPK1 | |
| SCHEMBL1813597 | 0.74 | CHRNA7 (0.40) | DRD2DRD3MAPTMEN1CYP2C19 | |
| SCHEMBL188681 | 0.74 | NCF1 (0.39) | DRD2DRD3MAPTNCF1MAPK1 | |
| SCHEMBL27749353 | 0.73 | NCF1 (0.37) | DRD2DRD3HTR6NCF1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101432284-A | Dihydropyrazolopyrimidinone derivative | BANYU PHARMA CO LTD (JP) | 2009-05-13 | — | — | CN | disclosed |