Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27749430 | 0.86 | LMNA (0.54) | TSHRMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL27858487 | 0.83 | KDM4E (0.54) | TSHRMEN1KMT2ACCR2 | |
| SCHEMBL2175966 | 0.78 | TSHR (0.72) | TSHRMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL3980968 | 0.75 | MEN1 (0.67) | TSHRMEN1KMT2A | |
| SCHEMBL7589375 | 0.75 | MEN1 (0.77) | TSHRMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL29833597 | 0.73 | ALDH1A1 (0.55) | TSHRMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL12407080 | 0.73 | LMNA (0.55) | TSHRMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL28728692 | 0.73 | ALDH1A1 (0.55) | TSHRMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL21497038 | 0.72 | KMT2A (0.59) | TSHRMEN1KMT2A | |
| SCHEMBL1471525 | 0.72 | MEN1 (0.62) | TSHRMEN1KMT2ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500554-B | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-06-27 | — | — | CN | disclosed |
| CN-101500554-A | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-08-05 | — | — | CN | disclosed |