Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | LOX | P28300 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKLR | P30613 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14486413 | 0.89 | PKM (1.00) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL835692 | 0.89 | PKM (1.00) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL13074716 | 0.89 | PKM (1.00) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL18069681 | 0.83 | PKM (0.86) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL19008825 | 0.83 | PKM (0.86) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL17472319 | 0.83 | PKM (0.86) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL14148915 | 0.83 | PKM (0.86) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL3223 | 0.82 | — | — | |
| SCHEMBL13665511 | 0.81 | PKM (0.83) | PKMGAARAPGEF4HSD11B1HTT | |
| SCHEMBL825670 | 0.81 | PKM (0.83) | PKMGAARAPGEF4HSD11B1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489555-A | Nf-kappa | OTSUKA PHARMA CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |