SCHEMBL3223

SCHEMBL3223

[CH2]c1ccc(OC)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10598384 0.97 CA1 (0.65)
SCHEMBL20913241 0.97 CA1 (0.65)
SCHEMBL2096923 0.92 LTA4H (0.61)
SCHEMBL2093349 0.92 ESR2 (0.58)
SCHEMBL8438727 0.87 HPGD (0.55)
SCHEMBL8582803 0.85 APP (0.63)
SCHEMBL2017201 0.85 PTGS2 (0.53)
SCHEMBL40356 0.85 PTGS2 (0.53)
SCHEMBL6291456 0.85 LTA4H (0.65)
1,4-Dimethoxybenzene SCHEMBL8489 0.83 CA1 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 73914 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384031-B1 None US claimed
CN-114644568-B Purification method of sitagliptin intermediate 浙江医药股份有限公司新昌制药厂 2024-07-19 CN claimed
WO-2024149366-A1 METHOD FOR PREPARING INTERMEDIATE OF ROCK INHIBITOR 武汉朗来科技发展有限公司 2024-07-18 WO claimed
US-20240240114-A1 Improved Combination of Protease and Protease Inhibitor with Secondary Enzyme BASF SE (DE) 2024-07-18 US claimed
EP-4039690-B1 A SUBSTANTIALLY DIASTEREOMERICALLY PURE PHOSPHORAMIDOCHLORIDATE, A METHOD AND A PHARMACEUTICAL COMPOSITION EISAI R&D MAN CO LTD (JP) 2024-07-17 EP claimed
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
EP-4399206-A1 PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES Redona Therapeutics, Inc. (US) 2024-07-17 EP claimed
CN-118344265-A Amide compound and preparation method and application thereof 河北大学 2024-07-16 CN claimed
CN-118344340-A Quinolinone compound containing 1,2, 4-triazole or 1,3, 4-oxadiazole structure and preparation and application thereof 贵州大学 2024-07-16 CN claimed
CN-118324695-A Method for selectively preparing quinoline-2-ketone or 3, 4-dihydro-quinoline-2-ketone compound under regulation of photocatalyst 浙江工业大学 2024-07-12 CN claimed
US-3957811-A Process for 3-(1-[arylmethyl]tetrazol-5-yl)penams PFIZER INC. (US) 1976-05-18 US claimed
US-3953436-A 3,4-Dicarboxycephalosporins and derivatives ELI LILLY AND COMPANY (US) 1976-04-27 US claimed
US-3946005-A BACTERICIDES SMITHKLINE CORPORATION (US) 1976-03-23 US claimed
US-3943129-A BACTERICIDE SMITHKLINE CORPORATION (US) 1976-03-09 US claimed
US-3943126-A Process for acylating a 7-aminocephalosporin ELI LILLY AND COMPANY (US) 1976-03-09 US claimed
US-3936446-A Isocyanocephalosporanates BEECHAM GROUP LIMITED (DT) 1976-02-03 US claimed
US-3936447-A 7-Acylamino-desacetoxy-cephalosporanic acid esters and their production BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed
US-3932393-A 3-Methylenecephalosporins and process for production thereof ELI LILLY AND COMPANY (US) 1976-01-13 US claimed
US-3932387-A Process for the conversion of 3-methyl-3-hydroxycepham compounds ELI LILLY AND COMPANY (US) 1976-01-13 US claimed
US-3931140-A (H-gly-gly-tyr-ala)1 -somatostatin AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US claimed