Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.52 |
| ▸ | ATP4A | P20648 | 4/20 | 0.50 |
| ▸ | ATP4B | P51164 | 4/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10305003 | 0.81 | ATP4A (0.51) | CYP19A1ATP4AATP4BKMT2AMAPT | |
| SCHEMBL27791621 | 0.78 | KDM4E (0.50) | CYP19A1ATP4AATP4BCYP1A1CYP1A2 | |
| SCHEMBL4437476 | 0.77 | CYP19A1 (0.57) | CYP19A1ATP4AATP4BCYP1A1CYP1A2 | |
| SCHEMBL28979459 | 0.77 | ATP4A (0.55) | CYP19A1ATP4AATP4BCYP1A1CYP1A2 | |
| SCHEMBL38240 | 0.75 | HSD17B10 (0.62) | CYP19A1ATP4AATP4BL3MBTL1LMNA | |
| SCHEMBL30123146 | 0.75 | HSD17B10 (0.62) | CYP19A1ATP4AATP4BL3MBTL1LMNA | |
| SCHEMBL6017146 | 0.75 | ALDH1A1 (0.55) | F2RL3LMNAKMT2AMAPTNPC1 | |
| SCHEMBL3772673 | 0.75 | CYP19A1 (0.58) | CYP19A1ATP4AATP4BCYP1A1CYP1A2 | |
| SCHEMBL30378574 | 0.75 | CYP19A1 (0.58) | CYP19A1ATP4AATP4BCYP1A1CYP1A2 | |
| Bromide SCHEMBL1915171 | 0.74 | HSD17B10 (0.61) | CYP19A1ATP4AATP4BL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646660-A | Compounds and methods for modulating G protein-coupled receptors | IRM LLC VG | 2010-02-10 | — | — | CN | disclosed |