Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | ATP4A | P20648 | 3/20 | 0.55 |
| ▸ | ATP4B | P51164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30378574 | 1.00 | CYP19A1 (0.58) | CYP19A1ATP4AATP4BNPC1RAB9A | |
| SCHEMBL3766189 | 0.85 | HTR2C (0.48) | CYP19A1ATP4AATP4BNPC1RAB9A | |
| SCHEMBL38240 | 0.81 | HSD17B10 (0.62) | CYP19A1ATP4AATP4BNPC1RAB9A | |
| SCHEMBL30123146 | 0.81 | HSD17B10 (0.62) | CYP19A1ATP4AATP4BNPC1RAB9A | |
| SCHEMBL4437476 | 0.79 | CYP19A1 (0.57) | CYP19A1ATP4AATP4BNPC1RAB9A | |
| SCHEMBL4437473 | 0.79 | CYP19A1 (0.57) | CYP19A1ATP4AATP4BNPC1RAB9A | |
| SCHEMBL27751529 | 0.79 | ATP4A (0.58) | CYP19A1ATP4AATP4BNPC1RAB9A | |
| SCHEMBL12067391 | 0.79 | CYP19A1 (0.57) | CYP19A1ATP4AATP4BNPC1RAB9A | |
| Bromide SCHEMBL1915171 | 0.79 | HSD17B10 (0.61) | CYP19A1ATP4AATP4BNPC1RAB9A | |
| SCHEMBL203816 | 0.79 | CYP19A1 (0.56) | CYP19A1ATP4AATP4BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769544-A | Polysubstituted thiazole derivative and application thereof in disease treatment | 上海汇伦医药股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115701427-A | Polysubstituted thiazole derivatives and their use in the treatment of diseases | 上海汇伦医药股份有限公司 | 2023-02-10 | — | — | CN | disclosed |
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20080312226-A1 | Amide Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | disclosed |
| CN-101103007-A | Amide compound | TAKEDA PHARMACEUTICAL (JP) | 2008-01-09 | — | — | CN | disclosed |
| EP-1813606-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312226-A1 | Amide Compound | FAAH, FAAH2, CNR2 | CYP19A1 788/4885ATP4A 1719/4885ATP4B 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.