Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 13/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2441087 | 0.87 | LIMK1 (0.44) | LIMK1HDAC1HDAC6AVPR2AVPR1A | |
| SCHEMBL28815683 | 0.77 | LOXL2 (0.55) | — | |
| SCHEMBL2443835 | 0.73 | CTSA (0.36) | LIMK1AVPR2AVPR1A | |
| SCHEMBL2440919 | 0.71 | LIMK1 (0.48) | LIMK1HDAC1HDAC6MAPK14 | |
| SCHEMBL38544 | 0.71 | LIMK1 (0.72) | LIMK1HDAC1HDAC6MAPK14KDM4E | |
| SCHEMBL30513213 | 0.71 | LIMK1 (0.72) | LIMK1HDAC1HDAC6MAPK14KDM4E | |
| SCHEMBL16513196 | 0.71 | LIMK1 (0.43) | LIMK1HDAC1HDAC6MAPK14LIMK2 | |
| SCHEMBL16513199 | 0.71 | LIMK1 (0.64) | LIMK1LIMK2 | |
| SCHEMBL28781561 | 0.70 | LIMK1 (0.43) | LIMK1HDAC1HDAC6MAPK14LIMK2 | |
| SCHEMBL16513235 | 0.69 | LIMK1 (0.41) | LIMK1HDAC1HDAC6AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646660-A | Compounds and methods for modulating G protein-coupled receptors | IRM LLC VG | 2010-02-10 | — | — | CN | disclosed |