Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 9/20 | 0.72 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38544 | 1.00 | LIMK1 (0.72) | LIMK1MAPK14KDM4EALDH1A1HPGD | |
| SCHEMBL16513215 | 0.85 | LIMK1 (1.00) | LIMK1MAPK14KDM4EALDH1A1HPGD | |
| SCHEMBL19981533 | 0.81 | LIMK1 (0.55) | LIMK1MAPK14KDM4EALDH1A1HPGD | |
| SCHEMBL11953304 | 0.81 | LIMK1 (0.54) | LIMK1MAPK14KDM4EALDH1A1HSD17B10 | |
| SCHEMBL2404342 | 0.78 | ALDH1A1 (0.53) | LIMK1MAPK14KDM4EALDH1A1NPC1 | |
| SCHEMBL2440919 | 0.78 | LIMK1 (0.48) | LIMK1MAPK14HDAC1HDAC6POLB | |
| SCHEMBL29993395 | 0.78 | ALDH1A1 (0.53) | LIMK1MAPK14KDM4EALDH1A1NPC1 | |
| SCHEMBL6001850 | 0.76 | MAPK14 (1.00) | LIMK1MAPK14KDM4E | |
| SCHEMBL11965510 | 0.75 | LIMK1 (0.46) | LIMK1MAPK14HDAC1HDAC6 | |
| SCHEMBL31063632 | 0.75 | ALDH1A1 (0.51) | LIMK1MAPK14KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111592534-B | New compounds | 特殊治疗有限公司 | 2023-06-30 | — | — | CN | disclosed |