SCHEMBL38544

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30513213	1.00	LIMK1 (0.72)	LIMK1MAPK14KDM4EALDH1A1HPGD
	SCHEMBL16513215	0.85	LIMK1 (1.00)	LIMK1MAPK14KDM4EALDH1A1HPGD
	SCHEMBL19981533	0.81	LIMK1 (0.55)	LIMK1MAPK14KDM4EALDH1A1HPGD
	SCHEMBL11953304	0.81	LIMK1 (0.54)	LIMK1MAPK14KDM4EALDH1A1HSD17B10
	SCHEMBL2404342	0.78	ALDH1A1 (0.53)	LIMK1MAPK14KDM4EALDH1A1NPC1
	SCHEMBL2440919	0.78	LIMK1 (0.48)	LIMK1MAPK14HDAC1HDAC6POLB
	SCHEMBL29993395	0.78	ALDH1A1 (0.53)	LIMK1MAPK14KDM4EALDH1A1NPC1
	SCHEMBL6001850	0.76	MAPK14 (1.00)	LIMK1MAPK14KDM4E
	SCHEMBL11965510	0.75	LIMK1 (0.46)	LIMK1MAPK14HDAC1HDAC6
	SCHEMBL31063632	0.75	ALDH1A1 (0.51)	LIMK1MAPK14KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.