Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | TYK2 | P29597 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253031 | 0.94 | RAB9A (0.62) | HTTJAK2TYK2RAB9ASIRT1 | |
| SCHEMBL3377974 | 0.94 | RAB9A (0.55) | HTTJAK2TYK2RAB9ASIRT1 | |
| SCHEMBL13701946 | 0.84 | GAA (0.63) | HTTJAK2TYK2SIRT1KCNK3 | |
| SCHEMBL8769758 | 0.84 | ALDH1A1 (0.55) | HTTRAB9ASIRT1KDM4EALDH1A1 | |
| SCHEMBL8770154 | 0.84 | MEN1 (0.55) | HTTRAB9ASIRT1NPC1KDM4E | |
| Acetanilide SCHEMBL27770851 | 0.84 | HSD17B10 (0.58) | HTTRAB9ANPC1ALDH1A1HDAC4 | |
| Bicarbonate SCHEMBL10672835 | 0.81 | NOTUM (0.57) | NPC1KAT6AKDM4EALDH1A1HDAC4 | |
| SCHEMBL3871686 | 0.80 | GCGR (0.59) | RAB9ANPC1NAMPTKDM4EALDH1A1 | |
| SCHEMBL13701850 | 0.79 | RAB9A (0.54) | HTTRAB9ANPC1KDM4EALDH1A1 | |
| N-Phenylbenzamide SCHEMBL28147891 | 0.79 | SIRT1 (0.80) | HTTJAK2TYK2RAB9ASIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101633841-B | Amido metal iridium complex electrophosphorescent luminescent material adopting phenylpyrazole main ligand and preparation thereof | UNIV JIANGNAN | 2013-07-17 | — | — | CN | disclosed |
| CN-101633841-A | Amido metal iridium complex electrophosphorescent luminescent material adopting phenylpyrazole main ligand and preparation thereof | UNIV JIANGNAN | 2010-01-27 | — | — | CN | disclosed |