Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 10/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776855 | 0.82 | DPP4 (0.45) | KMT2ACACNA1BKCNH2 | |
| Hydrochloric Acid SCHEMBL2774352 | 0.81 | DPP4 (0.44) | KMT2ACACNA1BKCNH2 | |
| SCHEMBL2773426 | 0.81 | CCR1 (0.49) | CCR1KMT2ALMNATSHRCACNA1B | |
| SCHEMBL6523862 | 0.78 | MEN1 (0.41) | CCR1KMT2ACACNA1BHRH3 | |
| SCHEMBL2777758 | 0.77 | CCR1 (0.59) | CCR1KMT2ALMNATSHR | |
| SCHEMBL2776270 | 0.76 | CCR1 (0.48) | CCR1KMT2ALMNATSHRKCNH2 | |
| SCHEMBL2775803 | 0.76 | CCR1 (0.55) | CCR1KMT2ALMNATSHRHRH3 | |
| SCHEMBL2780495 | 0.76 | CCR1 (0.55) | CCR1KMT2ALMNATSHRHRH3 | |
| SCHEMBL2773596 | 0.76 | CCR1 (0.55) | CCR1KMT2ALMNATSHRKCNH2 | |
| SCHEMBL2774188 | 0.75 | CCR1 (0.57) | CCR1KMT2ALMNATSHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |