Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27750242 | 0.82 | HTR6 (0.35) | HTR6SLC6A2SLC6A4 | |
| SCHEMBL27750239 | 0.82 | HTR6 (0.35) | HTR6SLC6A2SLC6A4HDAC1HDAC2 | |
| SCHEMBL27771228 | 0.81 | HTR6 (0.52) | HTR6SLC6A2SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL27750201 | 0.81 | HTR6 (0.39) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3620066 | 0.78 | HTR6 (0.56) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL27750196 | 0.77 | HTR6 (0.42) | HTR6HTR1ADRD2HTR1DHTR1B | |
| Trifluoroacetic Acid SCHEMBL3625968 | 0.73 | HTR6 (0.53) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL27936044 | 0.70 | HTT (0.38) | HTR6SLC6A2SLC6A4HDAC1HDAC2 | |
| SCHEMBL3626256 | 0.67 | HTR6 (0.50) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL27844705 | 0.67 | ACP3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | disclosed |