Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677914 | 0.81 | HTR6 (0.42) | HTTMAPTNPSR1RAPGEF4TDP1 | |
| SCHEMBL28750987 | 0.78 | HTT (0.46) | HTTMAPTNPSR1RAPGEF4TDP1 | |
| SCHEMBL12096726 | 0.73 | HTR6 (0.63) | HTTMAPTNPSR1RAPGEF4TDP1 | |
| SCHEMBL27750239 | 0.73 | HTR6 (0.35) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27750242 | 0.73 | HTR6 (0.35) | HTR6SLC6A2SLC6A4PPARG | |
| SCHEMBL27936029 | 0.71 | RXRA (0.36) | HDAC10HDAC6PPARG | |
| SCHEMBL27771328 | 0.70 | HTR6 (0.38) | HTR6HDAC1HDAC2HDAC6SLC6A2 | |
| SCHEMBL27936043 | 0.68 | HDAC3 (0.42) | HTTMAPTNPSR1RAPGEF4TDP1 | |
| SCHEMBL29527994 | 0.67 | HTR6 (0.56) | HTTMAPTNPSR1RAPGEF4TDP1 | |
| SCHEMBL27867741 | 0.66 | HTR6 (0.42) | HTR6PPARGPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103554006-A | Use of indole derivatives as nurr-1 activators for the application thereof as a medicament for the treatment of parkinson's disease | FOURNIER LAB SA | 2014-02-05 | — | — | CN | disclosed |