Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR1D | P28221 | 3/20 | 0.42 |
| ▸ | HTR1B | P28222 | 3/20 | 0.42 |
| ▸ | HTR1F | P30939 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27750252 | 0.84 | HTR6 (0.39) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL27771123 | 0.84 | HTR6 (0.39) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL27771130 | 0.82 | HTR6 (0.57) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27771221 | 0.80 | HTR6 (0.57) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL27750201 | 0.78 | HTR6 (0.39) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL27771328 | 0.77 | HTR6 (0.38) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3622409 | 0.70 | HTR6 (0.77) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL27750248 | 0.69 | HTR6 (0.59) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL3617435 | 0.68 | HTR6 (0.55) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL28777481 | 0.68 | HDAC3 (0.35) | HTR6HTR1AHTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | disclosed |