Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.37 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | HAT1 | O14929 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771799 | 0.90 | PTGDR2 (0.39) | PTGDR2NR4A2HAT1EP300 | |
| SCHEMBL27771803 | 0.75 | NR4A2 (0.43) | SLC6A2HTR2AHTR2CNR4A2 | |
| SCHEMBL3164947 | 0.75 | HTR1A (0.53) | PTGDR2HTR2A | |
| SCHEMBL3175225 | 0.74 | PTGDR2 (0.49) | PTGDR2HTR2A | |
| SCHEMBL1759590 | 0.71 | NR4A2 (0.47) | NR4A2 | |
| SCHEMBL3176752 | 0.70 | PTGDR2 (0.70) | PTGDR2 | |
| SCHEMBL27771709 | 0.70 | NR4A2 (0.49) | NR4A2 | |
| SCHEMBL3176262 | 0.69 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL12678746 | 0.68 | PTGDR2 (0.66) | PTGDR2 | |
| SCHEMBL23126476 | 0.67 | PTGDR2 (0.51) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102442941-A | Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2012-05-09 | — | — | CN | disclosed |
| CN-101636386-A | Polycyclic acid compounds useful as CRTH2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2010-01-27 | — | — | CN | disclosed |