Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HAT1 | O14929 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771713 | 0.90 | PTGDR2 (0.48) | PTGDR2NR4A2HAT1EP300 | |
| SCHEMBL1759590 | 0.73 | NR4A2 (0.47) | NR4A2MAPTKMT2A | |
| SCHEMBL27771709 | 0.72 | NR4A2 (0.49) | NR4A2POLBALDH1A1MAPTKMT2A | |
| SCHEMBL3175912 | 0.72 | DAO (0.45) | PTGDR2POLBMAPTKMT2A | |
| SCHEMBL27771803 | 0.69 | NR4A2 (0.43) | NR4A2 | |
| SCHEMBL27909433 | 0.66 | NR4A2 (0.46) | NR4A2POLBALDH1A1MAPTKMT2A | |
| SCHEMBL5592328 | 0.66 | NR4A2 (0.49) | NR4A2KMT2A | |
| SCHEMBL28046327 | 0.66 | NR4A2 (0.49) | NR4A2 | |
| SCHEMBL3995062 | 0.66 | NR4A2 (0.72) | NR4A2 | |
| SCHEMBL9077031 | 0.65 | KMT2A (0.52) | POLBALDH1A1MAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102442941-A | Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2012-05-09 | — | — | CN | disclosed |
| CN-101636386-A | Polycyclic acid compounds useful as CRTH2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2010-01-27 | — | — | CN | disclosed |