Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759590 | 0.87 | NR4A2 (0.47) | NR4A2CREBBP | |
| SCHEMBL27771709 | 0.84 | NR4A2 (0.49) | NR4A2CREBBPMTNR1AMTNR1B | |
| SCHEMBL3995062 | 0.77 | NR4A2 (0.72) | NR4A2CREBBP | |
| SCHEMBL28046327 | 0.77 | NR4A2 (0.49) | NR4A2HTR2ACREBBPHTR2CHTR2B | |
| SCHEMBL5592328 | 0.77 | NR4A2 (0.49) | NR4A2CREBBP | |
| SCHEMBL27771713 | 0.75 | PTGDR2 (0.48) | NR4A2HTR2ASLC6A2HTR2C | |
| SCHEMBL1760252 | 0.74 | NR4A2 (0.47) | NR4A2CREBBP | |
| SCHEMBL27909433 | 0.74 | NR4A2 (0.46) | NR4A2CREBBP | |
| SCHEMBL28284795 | 0.73 | NR4A2 (0.49) | NR4A2CREBBP | |
| SCHEMBL9720220 | 0.73 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102442941-A | Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2012-05-09 | — | — | CN | disclosed |
| CN-101636386-A | Polycyclic acid compounds useful as CRTH2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2010-01-27 | — | — | CN | disclosed |