Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5009462 | 0.89 | L3MBTL1 (0.47) | L3MBTL1TSHRCHRNA7KMT2ALMNA | |
| SCHEMBL14010107 | 0.89 | L3MBTL1 (0.47) | L3MBTL1TSHRCHRNA7KMT2ALMNA | |
| SCHEMBL5009463 | 0.89 | L3MBTL1 (0.47) | L3MBTL1TSHRCHRNA7KMT2ALMNA | |
| SCHEMBL3041762 | 0.77 | L3MBTL1 (0.54) | PPARAL3MBTL1TSHRCA12CA9 | |
| SCHEMBL3041765 | 0.77 | L3MBTL1 (0.54) | PPARAL3MBTL1TSHRCA12CA9 | |
| SCHEMBL1422047 | 0.77 | KMT2A (0.49) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL5007090 | 0.77 | ALDH1A1 (0.52) | L3MBTL1TSHRALDH1A1MAPK1CHRNA7 | |
| SCHEMBL5007086 | 0.77 | ALDH1A1 (0.52) | L3MBTL1TSHRALDH1A1MAPK1CHRNA7 | |
| SCHEMBL600925 | 0.76 | L3MBTL1 (0.56) | L3MBTL1TSHRALDH1A1MAPK1KMT2A | |
| SCHEMBL600924 | 0.76 | L3MBTL1 (0.56) | L3MBTL1TSHRALDH1A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101448782-A | 11beta-hydroxysteroid dehydrogenase type 1 active compounds | NOVO NORDISK AS (US) | 2009-06-03 | — | — | CN | disclosed |