Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 5/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772016 | 0.84 | FFAR1 (0.43) | GPR84ELANESLC22A6KMT2ANR4A2 | |
| SCHEMBL28030915 | 0.84 | ELANE (0.42) | ELANESLC22A6ALDH1A1NR4A2CHEK1 | |
| SCHEMBL27772032 | 0.84 | NR4A2 (0.52) | GPR84ELANESLC22A6NR4A2CHEK1 | |
| SCHEMBL27708215 | 0.84 | CYP2A6 (0.44) | ELANESLC22A6NR4A2CHEK1HTR1D | |
| SCHEMBL27920584 | 0.83 | SLC22A6 (0.59) | GPR84SLC22A6MEN1KMT2AMAPT | |
| SCHEMBL27846785 | 0.81 | ELANE (0.39) | ELANESLC22A6MEN1KMT2AKDM4E | |
| SCHEMBL27584085 | 0.80 | ELANE (0.38) | ELANESLC22A6MAPTALDH1A1NR4A2 | |
| SCHEMBL27892284 | 0.79 | MTNR1A (0.41) | ELANESLC22A6MEN1KMT2AMAPT | |
| SCHEMBL27623623 | 0.77 | SLC22A6 (0.69) | GPR84ELANESLC22A6MAPTKDM4E | |
| SCHEMBL27584057 | 0.77 | BRPF1 (0.55) | ELANESLC22A6MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495449-A | 2-phenyl-indoles as prostaglandin D2 receptor antagonists | SANOFI AVENTIS (FR) | 2009-07-29 | — | — | CN | disclosed |