Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 6/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772015 | 0.84 | GPR84 (0.44) | GPR84ELANEHTR2ASLC22A6NR4A2 | |
| SCHEMBL27708215 | 0.83 | CYP2A6 (0.44) | ELANESLC22A6NR4A2CHEK1SLC6A4 | |
| SCHEMBL28030915 | 0.83 | ELANE (0.42) | ELANEHTR2ASLC22A6NR4A2CHEK1 | |
| SCHEMBL27772032 | 0.83 | NR4A2 (0.52) | GPR84ELANESLC22A6NR4A2CHEK1 | |
| SCHEMBL27846785 | 0.80 | ELANE (0.39) | ELANESLC22A6NR4A2CHEK1SLC6A4 | |
| SCHEMBL27892284 | 0.78 | MTNR1A (0.41) | ELANEHTR2ASLC22A6HTR2CHTR2B | |
| SCHEMBL27623623 | 0.76 | SLC22A6 (0.69) | GPR84ELANESLC22A6NR4A2CHEK1 | |
| SCHEMBL28167759 | 0.75 | FFAR1 (0.53) | FFAR1GPR84HTR2AHTR2CHTR2B | |
| SCHEMBL10165367 | 0.75 | GPR84 (0.46) | FFAR1GPR84HTR2AHTR2CHTR2B | |
| SCHEMBL20368796 | 0.73 | ELANE (0.54) | ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495449-A | 2-phenyl-indoles as prostaglandin D2 receptor antagonists | SANOFI AVENTIS (FR) | 2009-07-29 | — | — | CN | disclosed |