Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772443 | 1.00 | ALDH1A1 (0.49) | ALDH1A1ENPEPMEN1LMNAKMT2A | |
| SCHEMBL15692392 | 0.88 | ALDH1A1 (0.46) | ALDH1A1ENPEPMEN1LMNAKMT2A | |
| SCHEMBL3396691 | 0.88 | ALDH1A1 (0.46) | ALDH1A1ENPEPMEN1LMNAKMT2A | |
| SCHEMBL3396696 | 0.88 | ALDH1A1 (0.46) | ALDH1A1ENPEPMEN1LMNAKMT2A | |
| SCHEMBL21261623 | 0.87 | ALDH1A1 (0.45) | ALDH1A1ENPEPMEN1LMNAKMT2A | |
| SCHEMBL28540874 | 0.87 | ALDH1A1 (0.45) | ALDH1A1ENPEPMEN1LMNAKMT2A | |
| SCHEMBL24178173 | 0.86 | ALDH1A1 (0.64) | ALDH1A1ENPEPMEN1LMNAKMT2A | |
| SCHEMBL15692293 | 0.86 | ALDH1A1 (0.64) | ALDH1A1ENPEPMEN1LMNAKMT2A | |
| SCHEMBL30483707 | 0.84 | ALDH1A1 (0.51) | ALDH1A1ENPEPMEN1LMNAKMT2A | |
| SCHEMBL14298968 | 0.84 | PLA2G2A (0.42) | ALDH1A1ENPEPMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101896470-A | Dual-acting benzimidazole derivatives and their use as antihypertensive agents | THERAVANCE INC | 2010-11-24 | — | — | CN | disclosed |
| CN-101657424-A | Dual-action antihypertensive agent | THERAVANCE INC US | 2010-02-24 | — | — | CN | disclosed |