SCHEMBL3396696

SCHEMBL3396696

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nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
ENPEP Q07075 13/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 1/20 0.44
CTSD P07339 1/20 0.43
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3396691 1.00 ALDH1A1 (0.46) ALDH1A1ENPEPMEN1LMNAKMT2A
SCHEMBL32677554 0.92 ENPEP (0.40) ALDH1A1ENPEPMEN1LMNAKMT2A
SCHEMBL20769311 0.92 ENPEP (0.44) ALDH1A1ENPEP
SCHEMBL20769310 0.92 ENPEP (0.44) ALDH1A1ENPEP
SCHEMBL29582522 0.89 CTSD (0.45) ENPEPCTSD
SCHEMBL27772445 0.88 ALDH1A1 (0.49) ALDH1A1ENPEPMEN1LMNAKMT2A
SCHEMBL27772443 0.88 ALDH1A1 (0.49) ALDH1A1ENPEPMEN1LMNAKMT2A
SCHEMBL30051624 0.87 ALDH1A1 (0.50) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL31151823 0.87 GRIN2D (0.51) ENPEPCTSD
SCHEMBL15692392 0.86 ALDH1A1 (0.46) ALDH1A1ENPEPMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
US-20250152692-A1 IMMUNOGENS TARGETING ANTHRAX UNIV MICHIGAN REGENTS (US) 2025-05-15 US disclosed
EP-4440605-A1 IMMUNOGENS TARGETING ANTHRAX The Regents of The University of Michigan (US) 2024-10-09 EP disclosed
WO-2023102483-A1 IMMUNOGENS TARGETING ANTHRAX THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-06-08 WO disclosed
US-20220411475-A1 HYBRID VIRUS-LIKE PARTICLES AND USE THEREOF AS A THERAPEUTIC HEPATITIS B VACCINE VLP BIOTECH, INC. (US) 2022-12-29 US disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed
US-11235045-B2 Hybrid hepadnavirus cores carrying multiple malaria parasite epitopes VLP BIOTECH, INC. (US) 2022-02-01 US disclosed
EP-2248821-B1 SUBSTRATE FOR ASSAYING -GLUCAN AND/OR ENDOTOXIN AND ASSAY METHOD WAKO PURE CHEM IND LTD (JP) 2015-01-28 EP disclosed
EP-2248821-A1 SUBSTRATE FOR ASSAYING -GLUCAN AND/OR ENDOTOXIN AND ASSAY METHOD Wako Pure Chemical Industries, Ltd. (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP ALDH1A1 3596/4885ENPEP 18/4885MEN1 1217/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD ALDH1A1 4110/4885ENPEP 5/4885MEN1 1147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.