Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 2/20 | 0.70 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.66 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31484803 | 1.00 | HMGB1 (0.70) | HMGB1FOLH1DHODHALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL14247891 | 0.98 | HMGB1 (0.68) | HMGB1FOLH1DHODHALDH1A1ALOX15 | |
| SCHEMBL9839456 | 0.88 | FOLH1 (0.61) | HMGB1FOLH1DHODHALDH1A1ALOX15 | |
| SCHEMBL30365583 | 0.87 | FOLH1 (0.76) | HMGB1FOLH1ALDH1A1ALOX15TSHR | |
| SCHEMBL70392 | 0.87 | FOLH1 (0.76) | HMGB1FOLH1ALDH1A1ALOX15TSHR | |
| SCHEMBL1417089 | 0.86 | FOLH1 (0.59) | HMGB1FOLH1DHODHALDH1A1ALOX15 | |
| SCHEMBL2777290 | 0.85 | FOLH1 (0.58) | HMGB1FOLH1DHODHALDH1A1ALOX15 | |
| SCHEMBL731621 | 0.83 | HMGB1 (0.55) | HMGB1FOLH1ALDH1A1TAAR1TSHR | |
| SCHEMBL31721455 | 0.83 | FOLH1 (0.66) | HMGB1FOLH1DHODHALDH1A1ALOX15 | |
| Ethylene SCHEMBL18893737 | 0.83 | FOLH1 (0.70) | HMGB1FOLH1ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909044-A | Synthesis method of 2- (alkylamino) ethyl benzoate compound | 南京爱德程医药科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-108976140-A | A kind of Preparation Method And Their Intermediate of 2- amino -6- ethyl benzoate | 上海医药工业研究院 | 2018-12-11 | — | — | CN | claimed |
| US-8299225-B2 | Amidite for synthesizing modified nucleic acid and method for synthesizing modified nucleic acid | FUJITSU LIMITED (JP) | 2012-10-30 | — | — | US | claimed |
| US-20090062521-A1 | AMIDITE FOR SYNTHESIZING MODIFIED NUCLEIC ACID AND METHOD FOR SYNTHESIZING MODIFIED NUCLEIC ACID | FUJITSU LIMITED (JP) | 2009-03-05 | — | — | US | claimed |
| US-20080167459-A1 | Amidite for nucleic acid synthesis and nucleic acid synthesizing method | FUJITSU LIMITED (JP) | 2008-07-10 | — | — | US | claimed |
| EP-0254009-B1 | A PROCESS FOR PURIFYING DINITROANILINE HERBICIDES | AGAN CHEMICAL MANUFACTURERS LTD. (IL) | 1991-04-17 | — | — | EP | claimed |
| EP-3478725-B1 | MODIFIED CARBOHYDRATES, COMPOSITIONS COMPRISING THE SAME, AND METHODS OF MAKING AND USING THE SAME | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2022-08-10 | — | — | EP | disclosed |
| US-20210284655-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2021-09-16 | — | — | US | disclosed |
| US-20210284655-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2021-09-16 | — | — | US | disclosed |
| US-10981931-B2 | Libraries of heteroaryl-containing macrocyclic compounds and methods of making and using the same | CYCLENIUM PHARMA INC. (CA) | 2021-04-20 | — | — | US | disclosed |
| US-10981931-B2 | Libraries of heteroaryl-containing macrocyclic compounds and methods of making and using the same | CYCLENIUM PHARMA INC. (CA) | 2021-04-20 | — | — | US | disclosed |
| CN-111909044-A | Synthesis method of 2- (alkylamino) ethyl benzoate compound | 南京爱德程医药科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| US-10766970-B2 | Modified carbohydrates, compositions comprising the same, and methods of making and using the same | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2020-09-08 | — | — | US | disclosed |
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | disclosed |
| WO-1994007938-A1 | WATER-DISPERSIBLE POLYESTER RESINS AND PROCESS FOR THEIR PREPARATION | EASTMAN CHEMICAL COMPANY (US) | 1994-04-14 | — | — | WO | disclosed |
| EP-0254009-B1 | A PROCESS FOR PURIFYING DINITROANILINE HERBICIDES | AGAN CHEMICAL MANUFACTURERS LTD. (IL) | 1991-04-17 | — | — | EP | disclosed |
| US-4970343-A | CONTACTING IN LIQUID STATE WITH HYDROBROMIDE SALT OF AMINO-BENZOIC ACID ESTER, DEHYDRATING | AGAN CHEMICAL MANUFACTURERS LTD. (IL) | 1990-11-13 | — | — | US | disclosed |
| EP-0254009-A1 | A process for purifying dinitroaniline herbicides | AGAN CHEMICAL MANUFACTURERS LTD. (IL) | 1988-01-27 | — | — | EP | disclosed |
| US-4537992-A | ACYLHALIDES AND AMINOBENZOATE ESTERS | AGAN CHEMICAL MANUFACTURERS, LTD. (IL) | 1985-08-27 | — | — | US | disclosed |
| US-4132774-A | SUNSCREEN AGENTS | GAF CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167459-A1 | Amidite for nucleic acid synthesis and nucleic acid synthesizing method | GABBR2, RNGTT, BCAT2 | HMGB1 2761/4885FOLH1 1617/4885DHODH 351/4885 |
| US-20210284655-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | NCOA3, VDR, GRK3 | HMGB1 3179/4885FOLH1 2516/4885DHODH 2194/4885 |
| US-10981931-B2 | Libraries of heteroaryl-containing macrocyclic compounds and methods of making and using the same | NCOA3, VDR, GRK3 | HMGB1 3179/4885FOLH1 2516/4885DHODH 2194/4885 |
| US-10766970-B2 | Modified carbohydrates, compositions comprising the same, and methods of making and using the same | ALG1, ALG8, CHIA | HMGB1 323/4885FOLH1 1250/4885DHODH 3170/4885 |
| US-20090062521-A1 | AMIDITE FOR SYNTHESIZING MODIFIED NUCLEIC ACID AND METHOD FOR SYNTHESIZING MODIFIED NUCLEIC ACID | NSUN2, RNMT, ADAR | HMGB1 1272/4885FOLH1 2965/4885DHODH 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.