Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953005 | 0.88 | APP (0.45) | ALDH1A1TSHRAPPAOX1PDE4B | |
| SCHEMBL27773256 | 0.78 | APP (0.65) | ALDH1A1TSHRAPPAOX1FDPS | |
| SCHEMBL29956100 | 0.78 | KAT2B (0.50) | ALDH1A1TSHRAOX1RORCSMN1; SMN2 | |
| SCHEMBL13522989 | 0.78 | ALDH1A1 (0.68) | ALDH1A1TSHRAOX1PDE4BFDPS | |
| SCHEMBL22713946 | 0.78 | ALDH1A1 (0.68) | ALDH1A1TSHRAOX1PDE4BFDPS | |
| SCHEMBL28954258 | 0.76 | RORC (0.37) | RORC | |
| SCHEMBL29957120 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRAPPAOX1PDE4B | |
| SCHEMBL18519470 | 0.76 | HPGD (0.51) | ALDH1A1TSHRAOX1RORCHPGD | |
| SCHEMBL4944263 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TSHRPDE4BFDPSSMN1; SMN2 | |
| SCHEMBL30780930 | 0.74 | POLB (0.42) | PDE4BRORCPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |