Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.36 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136950 | 0.76 | BCL2 (0.46) | BCL2BCL2L1CYP11B1CYP11B2 | |
| SCHEMBL13920153 | 0.73 | SMN1; SMN2 (0.38) | CTRCALDH1A1LMNACALM1TAAR1 | |
| SCHEMBL567898 | 0.73 | CCNC (0.34) | — | |
| SCHEMBL26671372 | 0.70 | CALM1 (0.48) | CTRCALDH1A1LMNANPSR1CALM1 | |
| SCHEMBL13917362 | 0.69 | HTT (0.45) | LMNA | |
| SCHEMBL27711544 | 0.69 | PTPN1 (0.42) | BCL2BCL2L1CYP11B1CYP11B2 | |
| SCHEMBL27711545 | 0.69 | BCL2 (0.42) | BCL2BCL2L1CYP11B1CYP11B2 | |
| SCHEMBL18698064 | 0.67 | CCNC (0.35) | CA12CA1CA2CA9CA14 | |
| SCHEMBL27773839 | 0.67 | SMN1; SMN2 (0.40) | CA12CA1CA2CA9CA14 | |
| SCHEMBL25344432 | 0.66 | CA1 (0.46) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516369-A | Pyridinone diketo acids: inhibitors of HIV replication in combination therapy | UNIV GEORGIA (US) | 2009-08-26 | — | — | CN | disclosed |