Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711544 | 0.79 | PTPN1 (0.42) | BCL2BCL2L1CYP11B1CYP11B2ALOX5 | |
| SCHEMBL1136950 | 0.78 | BCL2 (0.46) | BCL2BCL2L1CYP11B1CYP11B2ALOX5 | |
| SCHEMBL29597381 | 0.73 | ELANE (0.55) | BCL2BCL2L1ELANECTSGCHUK | |
| SCHEMBL8056666 | 0.70 | BCL2L1 (0.57) | BCL2BCL2L1ELANECTSGCHUK | |
| SCHEMBL30462302 | 0.69 | ELANE (0.51) | BCL2BCL2L1ELANECTSGCHUK | |
| SCHEMBL11671133 | 0.69 | ELANE (0.51) | BCL2BCL2L1ELANECTSGCHUK | |
| SCHEMBL27773753 | 0.69 | CTRC (0.39) | BCL2BCL2L1CYP11B1CYP11B2 | |
| SCHEMBL27655698 | 0.68 | MAPT (0.43) | MEN1HPGDKMT2A | |
| SCHEMBL4859864 | 0.67 | BCL2 (0.53) | BCL2BCL2L1CYP11B1CYP11B2ALOX5 | |
| SCHEMBL87816 | 0.65 | KEAP1 (0.75) | BCL2BCL2L1ALOX5KEAP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128199-B | Monocyclic heterocycles as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2013-07-24 | — | — | CN | disclosed |
| CN-101128199-A | Monocyclic heterocycles as kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2008-02-20 | — | — | CN | disclosed |