Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19557168 | 0.92 | HSD11B1 (0.48) | ALDH1A1HSD11B1GLAL3MBTL1PKM | |
| SCHEMBL19557166 | 0.92 | HSD11B1 (0.48) | ALDH1A1HSD11B1GLAL3MBTL1PKM | |
| SCHEMBL12714 | 0.92 | HSD11B1 (0.48) | ALDH1A1HSD11B1GLAL3MBTL1PKM | |
| Acetamide SCHEMBL28922396 | 0.91 | ALDH1A1 (0.46) | ALDH1A1HSD11B1GLAL3MBTL1PKM | |
| SCHEMBL5489940 | 0.90 | HSD11B1 (0.46) | ALDH1A1HSD11B1GLAL3MBTL1PKM | |
| SCHEMBL5487496 | 0.90 | HSD11B1 (0.46) | ALDH1A1HSD11B1GLAL3MBTL1PKM | |
| SCHEMBL11460245 | 0.90 | HSD11B1 (0.46) | ALDH1A1HSD11B1GLAL3MBTL1PKM | |
| SCHEMBL5489644 | 0.90 | HSD11B1 (0.46) | ALDH1A1HSD11B1GLAL3MBTL1PKM | |
| Hydrochloric Acid SCHEMBL1061147 | 0.90 | L3MBTL1 (0.50) | ALDH1A1HSD11B1GLAL3MBTL1PKM | |
| SCHEMBL5487136 | 0.90 | HSD11B1 (0.46) | ALDH1A1HSD11B1GLAL3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104140468-B | A kind of cellulose mixed esters, preparation method and applications | 中国科学院化学研究所 | 2017-08-25 | — | — | CN | claimed |
| CN-104140468-A | Cellulose mixed ester and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2014-11-12 | — | — | CN | claimed |
| CN-104140468-B | A kind of cellulose mixed esters, preparation method and applications | 中国科学院化学研究所 | 2017-08-25 | — | — | CN | disclosed |
| CN-104140468-B | A kind of cellulose mixed esters, preparation method and applications | 中国科学院化学研究所 | 2017-08-25 | — | — | CN | disclosed |
| CN-104140468-A | Cellulose mixed ester and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2014-11-12 | — | — | CN | disclosed |
| CN-104140468-A | Cellulose mixed ester and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2014-11-12 | — | — | CN | disclosed |
| US-8354148-B2 | Optical compensation polarizing plate, image display unit and liquid crystal display unit | FUJIFILM CORPORATION (JP) | 2013-01-15 | — | — | US | disclosed |
| US-7671947-B2 | Optical film, optical compensation film, polarizing plate, liquid crystal display unit and self luminous display unit | FUJIFILM CORPORATION (JP) | 2010-03-02 | — | — | US | disclosed |
| US-20080309860-A1 | Optical Film, Optical Compensation Film, Polarizing Plate, Liquid Crystal Display Unit and Self Luminous Display Unit | FUJIFILM CORPORATION (JP) | 2008-12-18 | — | — | US | disclosed |
| US-7435461-B2 | Hydrolysis-condensation product of a hydrolyzable and polycondensable reactive metal compound; improved display unevenness; liquid crystal display | FUJIFILM CORPORATION (JP) | 2008-10-14 | — | — | US | disclosed |
| US-20070292635-A1 | Optical Compensation Polarizing Plate, Image Display Unit and Liquid Crystal Display Unit | FUJIFILM CORPORATION (JP) | 2007-12-20 | — | — | US | disclosed |
| WO-2005111675-A1 | OPTICAL COMPENSATION POLARIZING PLATE, IMAGE DISPLAY UNIT AND LIQUID CRYSTAL DISPLAY UNIT | FUJIFILM CORPORATION (JP) | 2005-11-24 | — | — | WO | disclosed |
| WO-2005111676-A1 | OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY UNIT AND SELF LUMINOUS DISPLAY UNIT | FUJIFILM CORPORATION (JP) | 2005-11-24 | — | — | WO | disclosed |
| US-20050186360-A1 | Cellulose acylate film | FUJI FILM PHOTO CO., LTD. (JP) | 2005-08-25 | — | — | US | disclosed |