Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322390 | 0.79 | RAB9A (0.49) | CYP3A4CYP3A5POLBTBK1HTT | |
| SCHEMBL17007678 | 0.75 | CYP3A4 (0.53) | CYP3A4CYP3A5POLBHTTMEN1 | |
| SCHEMBL31647258 | 0.75 | CYP3A4 (0.56) | CYP3A4CYP3A5POLBHTTMEN1 | |
| SCHEMBL16759086 | 0.74 | CYP3A4 (0.49) | CYP3A4CYP3A5POLBTBK1HTT | |
| SCHEMBL1338046 | 0.74 | TRPA1 (0.45) | ATMMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL29282350 | 0.73 | POLB (0.48) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL24328590 | 0.73 | MAPT (0.44) | CYP3A4CYP3A5POLBHTTATM | |
| SCHEMBL25189278 | 0.72 | MAPT (0.48) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31173938 | 0.72 | MAPT (0.48) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL24414298 | 0.71 | GPR119 (0.51) | CYP3A4CYP3A5POLBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679396-B | Triazolylaminopyrimidine compounds | LILLY CO ELI | 2012-06-06 | — | — | CN | disclosed |
| CN-101679396-A | Triazolylaminopyrimidine compounds | LILLY CO ELI | 2010-03-24 | — | — | CN | disclosed |