Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KLK3 | P07288 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | S100A4 | P26447 | 2/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550119 | 0.86 | TDP1 (0.78) | TDP1ALDH1A1TSHRSMN1; SMN2KLK3 | |
| SCHEMBL27775375 | 0.84 | TDP1 (0.58) | TDP1ALDH1A1TSHRSMN1; SMN2KLK3 | |
| SCHEMBL3538629 | 0.84 | TDP1 (0.58) | TDP1ALDH1A1TSHRSMN1; SMN2KLK3 | |
| SCHEMBL9550137 | 0.83 | TDP1 (0.56) | TDP1ALDH1A1TSHRSMN1; SMN2MAPK1 | |
| Benzene SCHEMBL28038982 | 0.82 | ALDH1A1 (1.00) | TDP1ALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL44392 | 0.82 | ALDH1A1 (1.00) | TDP1ALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL30196067 | 0.82 | ALDH1A1 (1.00) | TDP1ALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL7939736 | 0.81 | TSHR (0.69) | TDP1ALDH1A1TSHRSMN1; SMN2KLK3 | |
| SCHEMBL3535775 | 0.80 | TDP1 (0.53) | TDP1ALDH1A1TSHRSMN1; SMN2KLK3 | |
| Water SCHEMBL2045405 | 0.80 | ALDH1A1 (0.96) | TDP1ALDH1A1TSHRHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101365685-B | 2-(benzimidazol-1-yl)-acetamide biaryl derivatives and their use as inhibitors of the TRPV1 receptor | N.V. ORGANON (NL) | 2011-12-14 | — | — | CN | disclosed |
| CN-101365685-A | 2-(benzimidazol-1-yl)-acetamide biaryl derivatives and their use as inhibitors of the TRPV1 receptor | ORGANON NV (NL) | 2009-02-11 | — | — | CN | disclosed |
| EP-1457813-B1 | An improved electrochromic medium capable of producing a pre-selected color | GENTEX CORP (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-1457813-A2 | An improved electrochromic medium capable of producing a pre-selected color | Gentex Corporation (US) | 2004-09-15 | — | — | EP | disclosed |
| EP-0972227-B1 | AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR | GENTEX CORP (US) | 2004-07-14 | — | — | EP | disclosed |
| US-6037471-A | FOR ELECTROCHROMIC MIRRORS FOR MOTOR VEHICLES | GENTEX CORPORATION (US) | 2000-03-14 | — | — | US | disclosed |
| US-6020987-A | Electrochromic medium capable of producing a pre-selected color | GENTEX CORPORATION (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0972227-A1 | AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR | GENTEX CORPORATION (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5998617-A | MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR | GENTEX CORPORATION (US) | 1999-12-07 | — | — | US | disclosed |
| WO-1998044384-A1 | AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR | GENTEX CORPORATION (US) | 1998-10-08 | — | — | WO | disclosed |
| WO-1997006144-A1 | 2-CARBOCYCLIC AND 2-HETEROCYCLIC QUINOLINE-4-CARBOXYLIC ACIDS AND SALTS THEREOF USEFUL AS IMMUNOSUPPRESSIVE AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-02-20 | — | — | WO | disclosed |
| US-5578609-A | INHIBITORS OF DIHYDROOROTATE DEHYDROGENASE, ANTITUMOR, TREATMENT OF ORGAN REJECTION | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5523408-A | USED FOR TREATMENT OR PREVENTION OF ORGAN TRANSPLANT REJECTION, GRAFT VERSUS HOST DISEASE, CHRONIC INFLAMMATORY DISEASES LIKE PSORIASIS, RHEUMATOID ARTHRITIS IN MAMMAL | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| US-5200544-A | Acid generator, acid sensitive polymer; photosensitivity | AT&T BELL LABORATORIES (US) | 1993-04-06 | — | — | US | disclosed |
| US-5135838-A | Resin sensitive to UV radiation and a nitrobenzyl compound that generates an acid | AT&T BELL LABORATORIES (US) | 1992-08-04 | — | — | US | disclosed |