Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | GALR1 | P47211 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516241 | 0.85 | CA1 (0.39) | HCAR3HCAR2RARARARBRARG | |
| SCHEMBL27775543 | 0.85 | MCL1 (0.39) | RARARARBRARG | |
| SCHEMBL28056804 | 0.85 | CA1 (0.39) | HCAR2RARARARBRARG | |
| SCHEMBL28186443 | 0.82 | NCOA1 (0.44) | HCAR2 | |
| SCHEMBL27975975 | 0.80 | LIPG (0.33) | RARARARBRARG | |
| SCHEMBL27775494 | 0.76 | RARB (0.31) | RARBRARG | |
| SCHEMBL27413672 | 0.76 | RXFP1 (0.35) | — | |
| SCHEMBL27371651 | 0.76 | BCL2L1 (0.38) | HCAR3HCAR2RARARARBRARG | |
| SCHEMBL28185749 | 0.76 | RXRA (0.35) | — | |
| SCHEMBL28093247 | 0.76 | SRD5A1 (0.36) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679447-A | pyrimidodiazepinone derivative | KYOWA HAKKO KIRIN CO LTD | 2010-03-24 | — | — | CN | disclosed |