Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.77 |
| ▸ | CA6 | P23280 | 5/20 | 0.77 |
| ▸ | CA7 | P43166 | 5/20 | 0.77 |
| ▸ | CA9 | Q16790 | 5/20 | 0.77 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.77 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.77 |
| ▸ | CA2 | P00918 | 4/20 | 0.77 |
| ▸ | CA4 | P22748 | 4/20 | 0.77 |
| ▸ | CA5A | P35218 | 4/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | F13A1 | P00488 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | THPO | P40225 | 2/20 | 0.77 |
| ▸ | CASP2 | P42575 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | RECQL | P46063 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | CA3 | P07451 | 3/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Spermine SCHEMBL30446193 | 0.87 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL14965 | 0.87 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL288720 | 0.87 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL8514287 | 0.87 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL5375346 | 0.86 | CA12 (0.72) | CA12CA6CA7CA9CA14 | |
| SCHEMBL3175232 | 0.84 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL4288395 | 0.84 | CA12 (0.93) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL348194 | 0.84 | UBE2N (1.00) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8092274 | 0.84 | CA12 (0.93) | CA12CA6CA7CA9CA14 | |
| SCHEMBL14739092 | 0.84 | CA12 (0.93) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302877-A | Quinazolinyl compounds and methods of use | 基因泰克公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-113508115-A | Pyridopyrimidinone and pteridinone compounds as inhibitors of endoribonuclease inositol requiring enzyme I (IRE I A) for the treatment of cancer diseases | 基因泰克公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-112689528-A | Pyrimidinyl-heteroaryloxy-naphthyl compounds and methods of use | 基因泰克公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-106795151-A | Protein kinase C inhibitors and methods of their use | 诺华股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-103189378-B | As the Pyrazolopyridine ketone derivatives of LPA receptor antagonist | MERCK PATENT GMBH (DE) | 2016-03-02 | — | — | CN | disclosed |
| CN-101679266-B | PIM kinase inhibitors and methods of their use | NOVARTIS AG | 2015-05-06 | — | — | CN | disclosed |
| CN-103189378-A | Pyrazolopyridinone derivatives as LPA receptor antagonists | MERCK PATENT GMBH | 2013-07-03 | — | — | CN | disclosed |
| CN-101679266-A | PIM kinase inhibitors and methods of their use | NOVARTIS AG | 2010-03-24 | — | — | CN | disclosed |